Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23332277 | 1.00 | TDP1 (0.77) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL12294526 | 1.00 | TDP1 (0.77) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL5379059 | 0.92 | PTPN1 (0.73) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL31301140 | 0.92 | PTPN1 (0.73) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL71401 | 0.92 | PTPN1 (0.73) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL71402 | 0.92 | PTPN1 (0.73) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL2627847 | 0.92 | PTPN1 (0.73) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| SCHEMBL16687613 | 0.92 | TDP1 (0.65) | TDP1PTPN1ALDH1A1MAPTLMNA | |
| 4-Methylbenzoic Acid Methyl Ester SCHEMBL10539663 | 0.88 | TDP1 (1.00) | TDP1ALDH1A1MAPTLMNANPC1 | |
| 4-Methylbenzoic Acid Methyl Ester SCHEMBL137891 | 0.88 | TDP1 (1.00) | TDP1ALDH1A1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287448-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-28 | — | — | EP | disclosed |