SCHEMBL1991032

SCHEMBL1991032

CCCCCCCCCCc1ccccc1C12C=CC=CC1O2.[Na]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.39
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
CYSLTR2 Q9NS75 6/20 0.34
CYSLTR1 Q9Y271 6/20 0.34
BID P55957 3/20 0.32
MCL1 Q07820 3/20 0.32
BCL2L1 Q07817 2/20 0.32
BAK1 Q16611 2/20 0.32
KAT8 Q9H7Z6 2/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
EP300 Q09472 1/20 0.32
KAT2A Q92830 1/20 0.32
KAT2B Q92831 1/20 0.32
KAT5 Q92993 1/20 0.32
SAE1 Q9UBE0 1/20 0.32
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3751913 1.00 LIPG (0.39) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL9324282 1.00 LIPG (0.39) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL27813961 0.99 LIPG (0.40) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL11511336 0.68 LIPG (0.67) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL11607229 0.68 LIPG (0.67) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL15809821 0.66 LIPG (0.69) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL9699968 0.66 LIPG (0.69) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL6679764 0.66 LIPG (0.69) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL18496530 0.66 LIPG (0.69) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL2511612 0.66 LIPG (0.69) LIPGNR1H2NR1H3CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351837-B2 Subtilase variants NOVOZYMES A/S (DK) 2019-07-16 US disclosed
US-20170096654-A1 Subtilase Variants NOVOZYMES A/S (DK) 2017-04-06 US disclosed
US-9528100-B2 Subtilase variants NOVOZYMES A/S (DK) 2016-12-27 US disclosed
US-20150024990-A1 Subtilase Variants NOVOZYMES AS (DK) 2015-01-22 US disclosed
US-20140018283-A1 Subtilase Variants NOVOZYMES A/S (DK) 2014-01-16 US disclosed
US-8569035-B2 Subtilase variants NOVOZYMES A/S (DK) 2013-10-29 US disclosed
US-20130225466-A1 Subtilase Variants NOVOZYMES A/S (DK) 2013-08-29 US disclosed
US-20110152155-A1 SUBTILASE VARIANTS NOVOZYMES A/S (DK) 2011-06-23 US disclosed
EP-1409659-B1 SUBTILASE VARIANTS NOVOZYMES AS (DK) 2008-10-01 EP disclosed
US-20080167213-A1 Subtilase Variants NOVOZYMES A/S (DK) 2008-07-10 US disclosed
WO-1997024178-A1 POLYMERIC PARTICULATE MATERIALS AND COMPOSITIONS CONTAINING THEM ALLIED COLLOIDS LIMITED (GB) 1997-07-10 WO disclosed