Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 15/20 | 0.52 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702571 | 0.85 | NR1H4 (0.59) | NR1H4EIF4EBP1 | |
| SCHEMBL21574198 | 0.84 | NR1H4 (0.58) | NR1H4 | |
| SCHEMBL21574214 | 0.82 | NR1H4 (0.55) | NR1H4 | |
| SCHEMBL22299620 | 0.78 | NR1H4 (0.56) | NR1H4 | |
| SCHEMBL16702125 | 0.78 | NR1H4 (0.63) | NR1H4EIF4EBP1 | |
| SCHEMBL16701999 | 0.78 | NR1H4 (0.73) | NR1H4 | |
| SCHEMBL16703486 | 0.77 | NR1H4 (0.64) | NR1H4TTR | |
| SCHEMBL16709795 | 0.77 | NR1H4 (0.61) | NR1H4 | |
| SCHEMBL16702377 | 0.76 | NR1H4 (0.69) | NR1H4EIF4EBP1 | |
| SCHEMBL16702714 | 0.74 | NR1H4 (0.67) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |