Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574198 | 0.91 | NR1H4 (0.58) | NR1H4MAPTPOLB | |
| SCHEMBL19910377 | 0.82 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL21574217 | 0.81 | NR1H4 (0.63) | NR1H4MAPTPOLB | |
| SCHEMBL21574200 | 0.80 | NR1H4 (0.59) | NR1H4MAPTPOLB | |
| SCHEMBL21574219 | 0.78 | NR1H4 (0.55) | NR1H4MAPTPOLB | |
| SCHEMBL21574296 | 0.74 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL18198085 | 0.74 | NR1H4 (0.62) | NR1H4MAPTPOLB | |
| SCHEMBL16709825 | 0.73 | NR1H4 (0.79) | NR1H4MAPTPOLB | |
| SCHEMBL21574259 | 0.73 | NR1H4 (0.67) | NR1H4MAPTPOLB | |
| SCHEMBL18191629 | 0.73 | NR1H4 (0.67) | NR1H4MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288948-B1 | FUSED TRICYCLIC PYRAZOLE DERIVATIVES USEFUL FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2019-11-20 | — | — | EP | disclosed |