⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424173 | 0.89 | — | — | |
| SCHEMBL6045772 | 0.83 | — | — | |
| SCHEMBL6045394 | 0.79 | NPSR1 (0.33) | — | |
| SCHEMBL27743482 | 0.79 | — | — | |
| SCHEMBL1039509 | 0.78 | BTN3A1 (0.32) | — | |
| SCHEMBL10380113 | 0.76 | — | — | |
| SCHEMBL320910 | 0.76 | P2RY2 (0.31) | — | |
| SCHEMBL27915482 | 0.75 | PYGB (0.33) | — | |
| SCHEMBL27933879 | 0.75 | PYGB (0.33) | — | |
| SCHEMBL25388821 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617426-A1 | INHIBITOR OF HMGB PROTEIN-MEDIATED IMMUNE RESPONSE ACTIVATION, AND SCREENING METHOD | Japan Science and Technology Agency (JP) | 2013-07-24 | — | — | EP | claimed |
| US-20130183348-A1 | Inhibitor of HMGB Protein-Mediated Immune Response Activation, and Screening Method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-07-18 | — | — | US | claimed |
| CN-103096899-A | Inhibitor of hmgb protein-mediated immune response activation, and screening method | JAPAN SCIENCE & TECH AGENCY | 2013-05-08 | — | — | CN | claimed |
| WO-2008116165-A9 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY INC (US) | 2009-06-11 | — | — | WO | claimed |
| WO-2008116165-A2 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| US-20080066741-A1 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | HUNTER, CHARLES ERIC | 2008-03-20 | — | — | US | claimed |
| US-20060183886-A1 | Ligands to enhance cellular uptake of biomolecules | CELL WORKS THERAPEUTICS, INC., A DELAWARE CORPORATION | 2006-08-17 | — | — | US | claimed |
| EP-1409548-A4 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS THERAPEUTICS INC (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1409548-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | Cell Works Inc. (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2003067209-A2 | LIGANDS TO ENHANCE CELLULAR UPTAKE OF BIOMOLECULES | CELL WORKS INC. (US) | 2003-08-14 | — | — | WO | claimed |
| US-20030119724-A1 | Ligands to enhance cellular uptake of biomolecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-26 | — | — | US | claimed |
| US-20240123168-A1 | PRODUCT DELIVERY DEVICES AND METHODS | MUSTAPHA JIHAD A (US) | 2024-04-18 | — | — | US | disclosed |
| WO-2024073386-A1 | IMPLANTABLE MEDICAL DEVICE FOR THE DELIVERY OF A NUCLEIC ACID | CELANESE EVA PERFORMANCE POLYMERS LLC (US) | 2024-04-04 | — | — | WO | disclosed |
| CN-117616122-A | Antisense oligonucleotides (ASOs) for efficient and accurate RNA editing using endogenous Adenosine Deaminase (ADAR) acting on RNA | 艾伯哈特卡尔斯图宾根大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-117479837-A | RNAi nanoparticles and methods of use thereof in agriculture | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20050221293-A1 | DNA virus microRNA and methods for inhibiting same | ROCKEFELLER UNIVERSITY, THE | 2005-10-06 | — | — | US | disclosed |
| US-20050222067-A1 | DNA virus microRNA and methods for inhibiting same | THE ROCKEFELLER UNIVERSITY | 2005-10-06 | — | — | US | disclosed |
| US-20050221490-A1 | DNA virus microRNA and methods for inhibiting same | ROCKEFELLER UNIVERSITY, THE | 2005-10-06 | — | — | US | disclosed |
| WO-2005079397-A2 | ANTI-MICRORNA OLIGONUCLEOTIDE MOLECULES | ROCKEFELLER UNIVERSITY (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050182005-A1 | Anti-microRNA oligonucleotide molecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-08-18 | — | — | US | disclosed |