Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062131 | 0.96 | POLB (0.56) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL20664307 | 0.92 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL19917666 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17070345 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL19917680 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17072091 | 0.90 | POLB (0.51) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL19157855 | 0.89 | HTT (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL18621846 | 0.89 | POLB (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL689051 | 0.88 | POLB (0.62) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL21472345 | 0.88 | POLB (0.53) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |