Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062131 | 0.91 | POLB (0.56) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL689051 | 0.91 | POLB (0.62) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25945276 | 0.88 | TDP1 (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19912243 | 0.88 | POLB (0.53) | POLBAPEX1HTTTDP1PPARG | |
| SCHEMBL21254277 | 0.87 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL690787 | 0.87 | HTT (0.67) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL17070345 | 0.87 | POLB (0.52) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19917666 | 0.87 | POLB (0.52) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19917680 | 0.87 | POLB (0.52) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18621846 | 0.86 | POLB (0.49) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149109-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |