SCHEMBL19912437

SCHEMBL19912437

Cc1ccc(-c2ccc3c4ccccc4n(-c4cc(-c5cc(C)cc(C(F)(F)F)c5)c(-n5c6ccccc6c6ccc(-c7ccc(C)cc7)cc65)cc4C#N)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.40
KIF11 P52732 1/20 0.33
TACR1 P25103 2/20 0.31
PTPN5 P54829 1/20 0.31
PDE9A O76083 1/20 0.31
PDE1C Q14123 1/20 0.31
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
XDH P47989 1/20 0.30
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30
NR3C2 P08235 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912421 0.96 AR (0.38) ARKIF11TACR1XDH
SCHEMBL19917916 0.96 AR (0.41) ARKIF11TACR1PTPN5PDE9A
SCHEMBL19912439 0.95 AR (0.36) ARKIF11XDHNR3C1PGR
SCHEMBL19912417 0.94 AR (0.39) ARKIF11XDH
SCHEMBL19912427 0.93 AR (0.44) ARKIF11PTPN5KDM4EALDH1A1
SCHEMBL19918042 0.93 AR (0.36) ARKIF11TACR1XDHNR3C1
SCHEMBL19912408 0.93 KIF11 (0.35) ARKIF11KDM4EALDH1A1NR3C1
SCHEMBL19912433 0.93 AR (0.38) ARTACR1PTPN5PDE9APDE1C
SCHEMBL19917915 0.92 AR (0.44) ARKIF11MAOBMAOAXDH
SCHEMBL19912450 0.92 AR (0.37) ARXDHPGRCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4212/4885KIF11 3316/4885TACR1 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.