SCHEMBL19912538

SCHEMBL19912538

Cc1cccc(-c2ccc3c4ccc(-c5cccc(C)c5)cc4n(-c4cc(-c5cc(C)cc(C(F)(F)F)c5)cc(-n5c6cc(-c7cccc(C)c7)ccc6c6ccc(-c7cccc(C)c7)cc65)c4C#N)c3c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.44
KDM5B Q9UGL1 2/20 0.38
KDM4A O75164 1/20 0.38
PTPN5 P54829 1/20 0.35
POLB P06746 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA4 P48058 1/20 0.34
ICMT O60725 1/20 0.34
MAT2A P31153 1/20 0.33
SYK P43405 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
CTSS P25774 1/20 0.32
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2B Q13224 2/20 0.32
PIP4K2A P48426 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GABRP O00591 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903652 0.97 AR (0.45) ARKDM5BKDM4APTPN5POLB
SCHEMBL19912533 0.96 AR (0.41) ARKDM5BKDM4APTPN5POLB
SCHEMBL19912550 0.94 AR (0.35) ARKDM5BKDM4APOLBRXRA
SCHEMBL20617091 0.94 AR (0.43) ARKDM5BKDM4APTPN5POLB
SCHEMBL19912527 0.94 AR (0.37) ARKDM5BKDM4APTPN5ADORA1
SCHEMBL19912544 0.93 KDM5B (0.35) ARKDM5BKDM4APOLBRXRA
SCHEMBL19918030 0.93 SYK (0.41) ARKDM5BKDM4APTPN5POLB
SCHEMBL19903651 0.93 AR (0.42) ARKDM5BKDM4APTPN5POLB
SCHEMBL19912556 0.91 KIF11 (0.37) ARKDM5BKDM4APOLBRXRA
SCHEMBL19912534 0.91 AR (0.44) ARKDM5BKDM4APTPN5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4212/4885KDM5B 3810/4885KDM4A 2878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.