SCHEMBL19913239

SCHEMBL19913239

Cc1cccc(-c2ccc3c4ccc(-c5cccc(C)c5)cc4n(-c4cc(-c5cc(C)nc(C)c5)c(-n5c6cc(-c7cccc(C)c7)ccc6c6ccc(-c7cccc(C)c7)cc65)cc4C#N)c3c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.40
LRRK2 Q5S007 3/20 0.36
KDM4A O75164 1/20 0.36
KDM5B Q9UGL1 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
HIF1A Q16665 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
IMPDH2 P12268 1/20 0.35
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPK1 P28482 3/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913231 0.97 AR (0.38) ARLRRK2KDM4AKDM5BSMN1; SMN2
SCHEMBL19919557 0.92 AR (0.41) ARLRRK2KDM4AKDM5BSMN1; SMN2
SCHEMBL19919841 0.91 KDM5B (0.35) KDM5B
SCHEMBL19909514 0.91 CYP1A2 (0.40) SMN1; SMN2HIF1AKDM4EALDH1A1HPGD
SCHEMBL23487766 0.90 AR (0.39) ARLRRK2KDM4AKDM5BSMN1; SMN2
SCHEMBL19913261 0.90 ADORA2A (0.39) ARSMN1; SMN2HIF1AADORA2AALDH1A1
SCHEMBL19919641 0.90 AR (0.36) ARSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL19913242 0.89 GRIN1 (0.33) KDM5BSMN1; SMN2HIF1AIMPDH2KDM4E
SCHEMBL19909528 0.89 CYP1A2 (0.38) SMN1; SMN2HIF1AKDM4EALDH1A1HPGD
SCHEMBL19913220 0.88 KDM4E (0.34) KDM4EALDH1A1HPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 AR 4245/4885LRRK2 4345/4885KDM4A 4544/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 AR 4245/4885LRRK2 4345/4885KDM4A 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.