SCHEMBL19913290

SCHEMBL19913290

Cc1cc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5cc(C)cc(C(F)(F)F)c5)ccc43)c2-c2cc(-c3ccccc3)nc(-c3ccccc3)c2)cc(C(F)(F)F)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
HPGD P15428 2/20 0.34
ALDH1A1 P00352 2/20 0.34
RXRA P19793 1/20 0.34
RXRG P48443 1/20 0.34
GAA P10253 1/20 0.34
MYC P01106 1/20 0.34
MAT2A P31153 1/20 0.33
XDH P47989 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
PTGER4 P35408 1/20 0.33
SYK P43405 1/20 0.33
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919552 0.94 RXRA (0.36) KDM4EHPGDALDH1A1RXRARXRG
SCHEMBL19912476 0.92 RXRA (0.38) RXRARXRGMAT2APTGER4TACR1
SCHEMBL19912498 0.92 RXRA (0.36) RXRARXRGMAT2APTGER4SYK
SCHEMBL19913285 0.91 MYC (0.38) KDM4EHPGDALDH1A1MYCPPARG
SCHEMBL19912504 0.91 RXRA (0.36) RXRARXRGMAT2APTGER4SYK
SCHEMBL19912518 0.90 CYP1A2 (0.34) ALDH1A1RXRARXRGMAT2AADORA1
SCHEMBL19912485 0.89 AR (0.40) RXRARXRGMAT2APTGER4SYK
SCHEMBL19912488 0.89 AR (0.36) RXRARXRGMAT2APTGER4TACR1
SCHEMBL22822127 0.89 RXRA (0.38) RXRARXRGMAT2AXDHPTGER4
SCHEMBL19917947 0.89 RXRA (0.36) RXRARXRGPTGER4SYKTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed