Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914464 | 0.94 | MEN1 (0.47) | L3MBTL1SIGMAR1MEN1KMT2ATAAR1 | |
| SCHEMBL1928659 | 0.86 | — | — | |
| SCHEMBL7003873 | 0.83 | GPR84 (0.41) | GPR84HRH3 | |
| SCHEMBL23761900 | 0.82 | HDAC3 (0.34) | SIGMAR1GPR84HRH4HRH3 | |
| SCHEMBL8955030 | 0.81 | GPR84 (0.44) | HRH1GPR84HRH3 | |
| SCHEMBL22851623 | 0.80 | HRH4 (0.55) | GPR84HRH4HRH3 | |
| SCHEMBL214012 | 0.78 | GPR84 (0.56) | GPR84HRH3 | |
| SCHEMBL24245953 | 0.76 | HRH4 (0.44) | SIGMAR1HRH4HRH3 | |
| SCHEMBL16135390 | 0.76 | GPR84 (0.59) | GPR84 | |
| SCHEMBL7575666 | 0.76 | GPR84 (0.59) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039621-A1 | INHIBITION OF OLIG2 ACTIVITY | Curtana Pharmaceuticals, Inc. (US) | 2018-03-01 | — | — | WO | disclosed |