SCHEMBL19914912

SCHEMBL19914912

CN1CCC2=C(CC(Cl)C=C2)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13931736 0.71
SCHEMBL15932773 0.68 MAOA (0.38) MAOAMAOB
SCHEMBL13149748 0.68 MAOA (0.34) MAOAMAOB
SCHEMBL14432256 0.67 MAOA (0.36) MAOAMAOB
SCHEMBL8342845 0.67 MAOA (0.36) MAOAMAOB
SCHEMBL23346994 0.66 MAOA (0.32) MAOAMAOB
SCHEMBL27305448 0.64 MAOA (0.34) MAOAMAOB
SCHEMBL21351173 0.62 MAOA (0.32) MAOAMAOB
SCHEMBL24214431 0.61 MAOA (0.33) MAOAMAOB
SCHEMBL8342687 0.60 MAOA (0.44) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374796-B1 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, its salts, solvates or hydrates and its use for the treatment of CNS disorderes ARENA PHARM INC (US) 2018-02-28 EP disclosed