SCHEMBL19916905

SCHEMBL19916905

Cc1sc2ccc3ccccc3c2c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
HPGD P15428 4/20 0.50
TSHR P16473 3/20 0.50
CYP3A4 P08684 2/20 0.50
RAB9A P51151 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HIF1A Q16665 2/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
ATM Q13315 1/20 0.50
CYP1A2 P05177 4/20 0.45
CYP2A6 P11509 3/20 0.45
PRNP P04156 1/20 0.41
ALDH1A1 P00352 6/20 0.41
TDP1 Q9NUW8 1/20 0.41
NQO1 P15559 1/20 0.39
NQO2 P16083 1/20 0.39
HNF4A P41235 1/20 0.38
HPRT1 P00492 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31216692 1.00 HSD17B10 (0.50) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL30062535 0.79 HSD17B10 (0.52) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL13250616 0.79 HSD17B10 (0.52) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL23625621 0.78 ALDH1A1 (0.44) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL12095329 0.78 TSHR (0.43) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL1193896 0.76 CYP3A4 (0.39) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL17858225 0.76 HPGD (0.42) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL17037122 0.75 HPRT1 (0.50) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL18810711 0.74 ALDH1A1 (0.50) HSD17B10HPGDTSHRCYP3A4RAB9A
SCHEMBL14295770 0.74 ALDH1A1 (0.50) HSD17B10HPGDTSHRCYP3A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10088749-B2 Photoacid-generating compound and associated polymer, photoresist composition, and method of forming a photoresist relief image ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-10-02 US disclosed
CN-107880016-A Photoacid generating compounds and related polymers, photoresist compositions, and methods of forming photoresist relief images 罗门哈斯电子材料有限责任公司 2018-04-06 CN disclosed
US-20180095363-A1 PHOTOACID-GENERATING COMPOUND AND ASSOCIATED POLYMER, PHOTORESIST COMPOSITION, AND METHOD OF FORMING A PHOTORESIST RELIEF IMAGE U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-04-05 US disclosed
WO-2018038464-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2018-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180095363-A1 PHOTOACID-GENERATING COMPOUND AND ASSOCIATED POLYMER, PHOTORESIST COMPOSITION, AND METHOD OF FORMING A PHOTORESIST RELIEF IMAGE PARN, ZYX, LBR HSD17B10 4767/4885HPGD 2302/4885TSHR 2422/4885
US-10088749-B2 Photoacid-generating compound and associated polymer, photoresist composition, and method of forming a photoresist relief image PARN, ZYX, LBR HSD17B10 4767/4885HPGD 2302/4885TSHR 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.