SCHEMBL19916978

SCHEMBL19916978

Bc1ccc2c(c1)Oc1ccc3ccccc3c1O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35
AHR P35869 4/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
HPRT1 P00492 1/20 0.33
HNF4A P41235 1/20 0.33
DPP4 P27487 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5407322 0.84 AHR (0.47) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL23633182 0.82 HSD17B10 (0.52) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL729622 0.82 HSD17B10 (0.52) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL19916879 0.80 AHR (0.61) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL19766243 0.80 HSD17B10 (0.50) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
Ethylene SCHEMBL27918467 0.78 HSD17B10 (0.48) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL19450358 0.78 AHR (0.54) ALDH1A1AHRKDM4E
SCHEMBL19916922 0.76 CA1 (0.47) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL19766245 0.74 HPRT1 (0.46) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6
SCHEMBL2029565 0.72 HPRT1 (0.61) CYP1A2CYP2C19HSD17B10ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038464-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2018-03-01 WO disclosed