SCHEMBL23633182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL729622	1.00	HSD17B10 (0.52)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL5407322	0.93	AHR (0.47)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL19766243	0.93	HSD17B10 (0.50)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL19766245	0.91	HPRT1 (0.46)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL2029565	0.89	HPRT1 (0.61)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL19916873	0.85	CYP2A6 (0.42)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL380655	0.84	HSD17B10 (0.46)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL6555247	0.83	KDM4E (0.46)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL19916879	0.82	AHR (0.61)	HSD17B10CYP2A6ALDH1A1TSHRTDP1
	SCHEMBL19916978	0.82	CYP1A2 (0.36)	HSD17B10CYP2A6ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.