Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 10/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19895134 | 0.91 | EGLN1 (0.63) | EGLN1FTOEGLN3EGLN2THRA | |
| SCHEMBL22369548 | 0.90 | EGLN1 (0.47) | EGLN1FTOEGLN3EGLN2 | |
| SCHEMBL22369546 | 0.86 | EGLN1 (0.45) | EGLN1FTOEGLN3EGLN2 | |
| SCHEMBL19895129 | 0.82 | ALPL (0.48) | EGLN1FTOEGLN3 | |
| SCHEMBL22369556 | 0.80 | EGLN1 (0.47) | EGLN1FTOEGLN3 | |
| SCHEMBL20109765 | 0.79 | EGLN1 (0.67) | EGLN1FTOEGLN3EGLN2THRA | |
| SCHEMBL19917277 | 0.78 | EGLN1 (0.61) | EGLN1FTOEGLN3THRATHRB | |
| SCHEMBL20109775 | 0.77 | EGLN1 (0.62) | EGLN1FTOTHRATHRB | |
| SCHEMBL20109769 | 0.76 | EGLN1 (0.60) | EGLN1FTOEGLN2THRATHRB | |
| SCHEMBL25934727 | 0.76 | EGLN1 (0.54) | EGLN1FTOEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287456-A1 | COMPOUND OF 5-HYDROXYL-1,7-NAPHTHYRIDINE SUBSTITUTED BY ARYL OR HETEROARYL, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF | Shenyang Sunshine Pharmaceutical Co., Ltd. (CN) | 2018-02-28 | — | — | EP | disclosed |