SCHEMBL19917367

SCHEMBL19917367

CCOC(=O)COCCC(C)(C)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TRPA1 O75762 1/20 0.39
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NLRP3 Q96P20 3/20 0.33
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644985 0.81 GAA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23651715 0.81 GAA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11163358 0.81 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL27357474 0.81 GAA (0.41) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21069035 0.80 CYP4F2 (0.38) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL436876 0.79 GAA (0.40) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6665142 0.79 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21069919 0.77 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1053009 0.77 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL364270 0.77 ALDH1A1 (0.54) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307429-B1 SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS TAKASAGO PERFUMERY CO LTD (JP) 2018-02-28 EP disclosed