Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917627 | 0.82 | TSHR (0.38) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL19917645 | 0.81 | HTT (0.32) | CHEK1CHEK2HTTBAZ2B | |
| SCHEMBL19917644 | 0.81 | HTT (0.31) | CHEK1CHEK2HTTBAZ2B | |
| SCHEMBL19917643 | 0.80 | BAZ2B (0.35) | CHEK1CHEK2HTTBAZ2B | |
| SCHEMBL19917539 | 0.80 | HTT (0.36) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL6370890 | 0.74 | BAZ2B (0.42) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL12395230 | 0.74 | BAZ2B (0.42) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL10313033 | 0.74 | BAZ2B (0.42) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL19899441 | 0.73 | MAPT (0.41) | CHEK1CHEK2HTTTSHRBAZ2B | |
| SCHEMBL12185503 | 0.72 | CHEK1 (0.42) | CHEK1CHEK2HTTTSHRBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018037230-A1 | PYRIDYL-ETHYLENEDIOXY-THIOPHENE DERIVATIVES AS TRANSPARENT CONDUCTIVE MATERIAL | UNIVERSITY OF STRATHCLYDE (GB) | 2018-03-01 | — | — | WO | disclosed |