Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30196015 | 1.00 | BCHE (0.44) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL30196318 | 1.00 | BCHE (0.44) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL21096627 | 1.00 | BCHE (0.44) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL19918228 | 0.99 | BCHE (0.43) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL29406787 | 0.99 | BCHE (0.43) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL30196010 | 0.96 | BCHE (0.46) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL19918214 | 0.96 | BCHE (0.46) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL19939654 | 0.94 | BCHE (0.44) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL19942821 | 0.92 | BCHE (0.44) | BCHESNCAKDM4ETP53MAPK1 | |
| SCHEMBL19918107 | 0.91 | SNCA (0.43) | BCHESNCAKDM4ETP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295101-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230295101-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-09-21 | — | — | US | disclosed |
| US-11560360-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-01-24 | — | — | US | disclosed |
| US-20200407333-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-12-31 | — | — | US | disclosed |
| US-10745366-B2 | Therapeutic compounds | ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190185441-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-06-20 | — | — | US | disclosed |
| WO-2018039487-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407333-A1 | THERAPEUTIC COMPOUNDS | CFTR, MC2R, RPS21 | BCHE 2894/4885SNCA 1861/4885KDM4E 4097/4885 |
| US-11560360-B2 | Therapeutic compounds | CFTR, MC2R, RPS21 | BCHE 2894/4885SNCA 1861/4885KDM4E 4097/4885 |
| US-20230295101-A1 | THERAPEUTIC COMPOUNDS | CFTR, C1R, FURIN | BCHE 1829/4885SNCA 2990/4885KDM4E 4078/4885 |
| US-20190185441-A1 | THERAPEUTIC COMPOUNDS | CFTR, C1R, FURIN | BCHE 1829/4885SNCA 2990/4885KDM4E 4078/4885 |
| US-10745366-B2 | Therapeutic compounds | CFTR, C1R, FURIN | BCHE 1829/4885SNCA 2990/4885KDM4E 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.