SCHEMBL19918599

SCHEMBL19918599

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccc(-c7ccc8oc9ccccc9c8c7)cc6c6c7cccc8c7c(cc65)-c5ccccc5-8)c4)n3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
PDE10A Q9Y233 1/20 0.32
PLA2G10 O15496 1/20 0.32
HPSE Q9Y251 2/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
CHEK2 O96017 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918597 0.99 PLA2G2A (0.32) PLA2G2APLA2G4APDE10APLA2G10HPSE
SCHEMBL19918608 0.98 PLA2G2A (0.34) PLA2G2APLA2G4APDE10APLA2G10HPSE
SCHEMBL19918603 0.98 PLA2G2A (0.34) PLA2G2APLA2G4APDE10APLA2G10HPSE
SCHEMBL19918604 0.95 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918596 0.94 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL19918602 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL19918619 0.94 PLA2G2A (0.36) PLA2G2APLA2G4APDE10APLA2G10HSP90AA1
SCHEMBL19918613 0.94 PLA2G2A (0.36) PLA2G2APLA2G4APDE10APLA2G10HSP90AA1
SCHEMBL19918620 0.93 PLA2G2A (0.37) PLA2G2APLA2G4APDE10APLA2G10HSP90AA1
SCHEMBL19918601 0.92 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed