SCHEMBL19918649

SCHEMBL19918649

c1ccc(-n2c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5c(c4)oc4ccccc45)cc3c3c4cccc5c4c(cc32)-c2ccccc2-5)cc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGER4 P35408 1/20 0.34
TSPO P30536 1/20 0.31
AHR P35869 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918626 0.94 KDM4E (0.36) KDM4EATML3MBTL1TSPOALOX5
SCHEMBL19918651 0.94 KDM4E (0.36) KDM4EATML3MBTL1TSPOALOX5
SCHEMBL19918526 0.94 KDM4E (0.36) KDM4EATML3MBTL1TSPOALOX5
SCHEMBL19918618 0.93 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL19918611 0.92 PTGER4 (0.34) KDM4EL3MBTL1PTGER4AHRALOX5
SCHEMBL19918622 0.91 KDM4E (0.34) KDM4EATML3MBTL1AHRALOX5
SCHEMBL19918616 0.90 KDM4E (0.35) KDM4EATML3MBTL1AHRALOX5
SCHEMBL19918571 0.89 PTGER4 (0.33) KDM4EATML3MBTL1PTGER4AHR
SCHEMBL19918655 0.88 L3MBTL1 (0.42) KDM4EATML3MBTL1PTGER4TSPO
SCHEMBL19918639 0.88 L3MBTL1 (0.42) KDM4EATML3MBTL1PTGER4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed