⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952221 | 0.59 | — | — | |
| SCHEMBL2270734 | 0.56 | — | — | |
| SCHEMBL16402844 | 0.56 | LOXL2 (0.33) | — | |
| SCHEMBL8512657 | 0.27 | HSP90AA1 (0.36) | — | |
| SCHEMBL28147 | 0.27 | — | — | |
| SCHEMBL31437084 | 0.27 | TSHR (0.50) | — | |
| Pyrazine SCHEMBL1226089 | 0.27 | TSHR (0.50) | — | |
| SCHEMBL10066089 | 0.27 | — | — | |
| SCHEMBL6304896 | 0.25 | — | — | |
| SCHEMBL301813 | 0.25 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1070 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776897-B2 | such as 3-[1-(5-chloro-2-thienyl)cyclopenty]-5,6,7,8,9,10-hexahydro [1,2,4]triazolo[4,3-a]azocine, having a strong 11 beta -hydroxysteroid dehydrogenase type 1inhibitory activity and exhibiting an excellent blood-glucose level-lowering action, used for the therapy of diabetes and insulin resistance | ASTELLAS PHARMA INC. (JP) | 2010-08-17 | — | — | US | claimed |
| US-7341606-B2 | Medium and bicyclic fused 5-5-membered aza heteroaromatic derivative having ring junction nitrogen and N-hydroxy or N-amino group as developer and coupler; safe; kits | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-11 | — | — | US | claimed |
| US-7288123-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-30 | — | — | US | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| EP-1796615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-06-20 | — | — | EP | claimed |
| EP-1790641-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-05-30 | — | — | EP | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| US-7192452-B2 | Pyrazolo-triazoles and use of said compounds for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2007-03-20 | — | — | US | claimed |
| US-20070050923-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | WELLA OPERATIONS US, LLC | 2007-03-08 | — | — | US | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| EP-0200354-B1 | Pyrazolo [3,2-c]-s-triazole photographic couplers, their use, synthesis and intermediates therefore | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-07-04 | — | — | EP | claimed |
| US-4929538-A | CONTAINING STABILIZER FOR CYAN IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| EP-0367498-A2 | Photographic material and process comprising a pyrazoloazole dyeforming coupler | EASTMAN KODAK COMPANY (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0367499-A2 | Photographic element and process | EASTMAN KODAK COMPANY (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0356925-A2 | Photographic element and process comprising a development inhibitor releasing coupler and a yellow dye-forming coupler | EASTMAN KODAK COMPANY (US) | 1990-03-07 | — | — | EP | claimed |
| US-4892805-A | ETHER SUBSTITUTED PYRAZOLOAZOLE COLOR COUPLERS | EASTMAN KODAK COMPANY (US) | 1990-01-09 | — | — | US | claimed |
| US-4835094-A | Color photographic recording material containing a color coupler of the pyrazoloazole series | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | claimed |
| US-4777121-A | PHOTOSTABILITY | EASTMAN KODAK COMPANY (US) | 1988-10-11 | — | — | US | claimed |
| EP-0240852-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1987-10-14 | — | — | EP | claimed |
| EP-0200354-A2 | Pyrazolo [3,2-c]-s-triazole photographic couplers, their use, synthesis and intermediates therefore | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-11-05 | — | — | EP | claimed |