Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623506 | 0.84 | GLS (0.44) | GLS | |
| SCHEMBL19919994 | 0.83 | GLS (0.59) | GLS | |
| SCHEMBL15042446 | 0.79 | GLS (1.00) | GLS | |
| SCHEMBL21368693 | 0.74 | GLS (0.72) | GLS | |
| SCHEMBL22623415 | 0.73 | GLS (0.46) | GLS | |
| SCHEMBL15727776 | 0.67 | GLS (0.76) | GLS | |
| SCHEMBL14987279 | 0.65 | GLS (1.00) | GLS | |
| SCHEMBL19920091 | 0.64 | GLS (0.45) | GLS | |
| SCHEMBL15727760 | 0.64 | GLS (0.76) | GLS | |
| SCHEMBL14987454 | 0.64 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039442-A1 | TREATMENT OF CANCER WITH INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-01 | — | — | WO | disclosed |