Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043789 | 0.86 | GLS (1.00) | GLS | |
| SCHEMBL21368571 | 0.84 | GLS (0.77) | GLS | |
| SCHEMBL15782779 | 0.83 | GLS (0.78) | GLS | |
| SCHEMBL14987019 | 0.81 | GLS (1.00) | GLS | |
| SCHEMBL15782611 | 0.80 | GLS (1.00) | GLS | |
| SCHEMBL14987565 | 0.79 | GLS (0.62) | GLS | |
| SCHEMBL14987160 | 0.79 | GLS (1.00) | GLS | |
| SCHEMBL16384722 | 0.79 | GLS (0.95) | GLS | |
| SCHEMBL16305204 | 0.78 | GLS (0.75) | GLS | |
| SCHEMBL14987291 | 0.77 | GLS (0.81) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277276-B1 | METHODS OF ADMINISTERING GLUTAMINASE INHIBITORS | CALITHERA BIOSCIENCES INC (US) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018039442-A1 | TREATMENT OF CANCER WITH INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-01 | — | — | WO | disclosed |