Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21937684 | 0.80 | — | — | |
| SCHEMBL16699893 | 0.79 | CYP2C19 (0.32) | — | |
| SCHEMBL15775058 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22615174 | 0.77 | — | — | |
| SCHEMBL1768062 | 0.75 | — | — | |
| SCHEMBL23369622 | 0.74 | — | — | |
| SCHEMBL23369783 | 0.74 | — | — | |
| SCHEMBL23369615 | 0.74 | THRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL27793068 | 0.73 | — | — | |
| SCHEMBL13640410 | 0.72 | POLB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039531-A1 | SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2018-03-01 | — | — | WO | disclosed |