Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618689 | 0.87 | L3MBTL1 (0.54) | TSHRL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18224253 | 0.79 | GLA (0.41) | TSHRL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6422035 | 0.79 | L3MBTL1 (0.54) | TSHRL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL11887748 | 0.77 | TSHR (1.00) | TSHRSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18036536 | 0.73 | CYP2C19 (0.44) | TSHRL3MBTL1CYP2C19POLB | |
| SCHEMBL31063970 | 0.72 | TSHR (0.69) | TSHRSMN1; SMN2L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL17767814 | 0.72 | L3MBTL1 (0.47) | TSHRL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18224252 | 0.69 | GLA (0.39) | TSHRL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10402245 | 0.69 | KMT2A (0.52) | TSHRL3MBTL1ALDH1A1KMT2ANPC1 | |
| SCHEMBL5907904 | 0.68 | MME (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075537-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROLOGIC DISORDERS | NEUROP, INC. (US) | 2011-06-23 | — | — | WO | disclosed |