Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220688 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| SCHEMBL9717389 | 0.87 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| SCHEMBL20606888 | 0.83 | IRAK4 (0.47) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL27961101 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| SCHEMBL254364 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| Hydrogen Peroxide SCHEMBL9514730 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| SCHEMBL134091 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| Benzene SCHEMBL28132022 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| SCHEMBL29657201 | 0.81 | ALDH1A1 (0.59) | ALDH1A1ALOX15TDP1GAAKMT2A | |
| Ammonia Solution, Strong SCHEMBL11877644 | 0.79 | ALDH1A1 (0.56) | ALDH1A1ALOX15TDP1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743491-B | Novel oxathiolanecarboxylic acids and derivatives thereof for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-08-21 | — | — | CN | disclosed |
| US-10183954-B2 | Oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection | HOFFMANN-LA ROCHE INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180065991-A1 | NOVEL OXATHIOLANE CARBOXYLIC ACIDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065991-A1 | NOVEL OXATHIOLANE CARBOXYLIC ACIDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | CXCR1, CCR1, SLC7A1 | ALDH1A1 23/4885ALOX15 579/4885TDP1 2353/4885 |
| US-10183954-B2 | Oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection | CXCR1, CCR1, HAVCR2 | ALDH1A1 16/4885ALOX15 618/4885TDP1 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.