SCHEMBL19922473

SCHEMBL19922473

Brc1ccc2c(c1)C1(c3ccccc3N(c3ccccc3)c3ccccc31)c1c-2ccc2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.31
DHFR P00374 2/20 0.31
CYP2A6 P11509 1/20 0.31
PGR P06401 1/20 0.31
EGFR P00533 1/20 0.30
ERBB2 P04626 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23930775 0.92 PDK2 (0.32) PDK2KDM4EMEN1MAPTMAPK1
SCHEMBL19922039 0.85 PGR (0.32) PDK2CYP2A6PGR
SCHEMBL12126537 0.85 PDK2 (0.42) PDK2MAPK1POLBPGR
SCHEMBL19797303 0.83 PDK2 (0.44) PDK2MEN1MAPTMAPK1KMT2A
SCHEMBL19822252 0.83 PDK2 (0.44) PDK2MEN1MAPTMAPK1KMT2A
SCHEMBL19921788 0.83 PDK2 (0.40) PDK2POLBCYP2A6PGR
SCHEMBL19007133 0.82 PDK2 (0.43) PDK2KDM4EMEN1MAPTMAPK1
SCHEMBL29461269 0.82 PDK2 (0.43) PDK2KDM4EMEN1MAPTMAPK1
SCHEMBL19921804 0.82 PGR (0.33) PDK2PGR
SCHEMBL25883301 0.81 PDK2 (0.34) PDK2KDM4EMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038401-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed