Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cedrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | THRB | P10828 | 1/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.84 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cedrol SCHEMBL22392315 | 0.95 | ALOX15 (0.87) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL30379407 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL107488 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL19414169 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL1866891 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL6510353 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL30399146 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL16440943 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL18603986 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| Cedrol SCHEMBL107489 | 0.92 | ALOX15 (1.00) | ALOX15ALDH1A1LMNATHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11944727-B2 | Air freshening device | GIVAUDAN SA (CH) | 2024-04-02 | — | — | US | disclosed |
| US-20210128770-A1 | AIR FRESHENING DEVICE | GIVAUDAN S.A. (CH) | 2021-05-06 | — | — | US | disclosed |
| US-10925992-B2 | Air freshening device | GIVAUDAN S.A. (CH) | 2021-02-23 | — | — | US | disclosed |
| US-20180064838-A1 | AIR FRESHENING DEVICE | GIVAUDAN S.A. (CH) | 2018-03-08 | — | — | US | disclosed |