⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16973676 | 0.97 | — | — | |
| SCHEMBL26768 | 0.97 | — | — | |
| SCHEMBL27894584 | 0.94 | — | — | |
| SCHEMBL28234960 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL21770 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL25294729 | 0.94 | — | — | |
| Bromide SCHEMBL10492849 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL28289604 | 0.94 | — | — | |
| Sulfuric Acid SCHEMBL5663602 | 0.87 | TSHR (0.55) | — | |
| SCHEMBL28049736 | 0.85 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778577-B1 | NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY | LG CHEMICAL LTD (KR) | 2023-08-30 | — | — | EP | disclosed |
| US-11447480-B2 | Compound exhibiting enteropeptidase inhibitory activity | LG CHEM, LTD. (KR) | 2022-09-20 | — | — | US | disclosed |
| US-20210284634-A1 | NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY | LG CHEM, LTD. (KR) | 2021-09-16 | — | — | US | disclosed |
| EP-3778577-A1 | NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY | LG CHEM, LTD. (KR) | 2021-02-17 | — | — | EP | disclosed |
| EP-3510022-B1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019216742-A1 | NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY | 주식회사 엘지화학 (KR) | 2019-11-14 | — | — | WO | disclosed |
| EP-3510022-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | Janssen Pharmaceutica NV (BE) | 2019-07-17 | — | — | EP | disclosed |
| US-10251864-B2 | Indole derivatives useful as glucagon receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2019-04-09 | — | — | US | disclosed |
| WO-2018048761-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-15 | — | — | WO | disclosed |
| US-20180064686-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-08 | — | — | US | disclosed |