Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721050 | 0.95 | — | — | |
| SCHEMBL1235539 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7548607 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7545025 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7541388 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7545108 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1701715 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3208419 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL22500035 | 0.93 | — | — | |
| SCHEMBL2822938 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188694-B | Sodium channel modulators for the treatment of pain | 卓莫赛尔公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105188694-A | Sodium channel modulators for the treatment of pain | CHROMOCELL CORP | 2015-12-23 | — | — | CN | disclosed |