Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3039754 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL1814460 | 0.92 | — | — | |
| Acetic Acid SCHEMBL11393720 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL27984532 | 0.88 | — | — | |
| Acetic Acid SCHEMBL11332773 | 0.88 | — | — | |
| Acetic Acid SCHEMBL28535319 | 0.85 | — | — | |
| Acetic Acid SCHEMBL28318602 | 0.85 | FFAR3 (0.54) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL11302189 | 0.83 | FFAR3 (0.44) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL28180219 | 0.81 | FFAR3 (0.50) | FFAR3LCKFYNTSHRLMNA | |
| Pyruvate SCHEMBL9721321 | 0.81 | FFAR3 (0.50) | FFAR3LCKFYNTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10799532-B2 | Treatment water of lifestyle-related diseases and method of treating the lifestyle-related diseases | Ichikawa, Yoshio (JP) | 2020-10-13 | — | — | US | disclosed |
| US-20180064756-A1 | TREATMENT WATER OF LIFESTYLE-RELATED DISEASES AND METHOD OF TREATING THE LIFESTYLE-RELATED DISEASES | Ichikawa, Yoshio (JP) | 2018-03-08 | — | — | US | disclosed |