Acetic Acid

Acetic Acid

SCHEMBL3039754

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nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.64
LCK P06239 1/20 0.64
FYN P06241 1/20 0.64
TSHR P16473 5/20 0.55
LMNA P02545 3/20 0.42
THPO P40225 1/20 0.39
ALDH1A1 P00352 4/20 0.38
CA1 P00915 3/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
SLC15A2 Q16348 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1814460 1.00
Acetic Acid SCHEMBL11393720 1.00 FFAR3 (0.64) FFAR3LCKFYNTSHRLMNA
Acetic Acid SCHEMBL27984532 0.96
Acetic Acid SCHEMBL11332773 0.96
Acetic Acid SCHEMBL19923337 0.92 FFAR3 (0.54) FFAR3LCKFYNTSHRLMNA
Acetic Acid SCHEMBL28535319 0.92
Acetic Acid SCHEMBL28318602 0.92 FFAR3 (0.54) FFAR3LCKFYNTSHRLMNA
Acetic Acid SCHEMBL28180219 0.89 FFAR3 (0.50) FFAR3LCKFYNTSHRLMNA
Pyruvate SCHEMBL9721321 0.89 FFAR3 (0.50) FFAR3LCKFYNTSHRLMNA
Bicarbonate SCHEMBL8827978 0.86 TSHR (0.60) FFAR3LCKFYNTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750199-B1 Kit systems for granulated decontamination formulations SANDIA CORPORATION (US) 2010-07-06 US claimed
WO-2005089100-A2 DECONTAMINATION FORMULATIONS FOR DISINFECTION AND STERILIZATION SANDIA CORPORATION (US) 2005-09-29 WO claimed
WO-2005057588-A2 GRANULATED DECONTAMINATION FORMULATIONS SANDIA CORPORATION (US) 2005-06-23 WO claimed
US-20050109981-A1 Decontamination formulations for disinfection and sterilization NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2005-05-26 US claimed
US-7750199-B1 Kit systems for granulated decontamination formulations SANDIA CORPORATION (US) 2010-07-06 US disclosed
US-20070249509-A1 GRANULATED DECONTAMINATION FORMULATIONS NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2007-10-25 US disclosed
US-7276468-B1 Granulated decontamination formulations SANDIA CORPORATION (US) 2007-10-02 US disclosed
US-7271137-B2 Decontamination formulations for disinfection and sterilization SANDIA CORPORATION (US) 2007-09-18 US disclosed
US-7125497-B1 Reactive formulations for a neutralization of toxic industrial chemicals SANDIA CORPORATION (US) 2006-10-24 US disclosed
WO-2005089100-A2 DECONTAMINATION FORMULATIONS FOR DISINFECTION AND STERILIZATION SANDIA CORPORATION (US) 2005-09-29 WO disclosed
WO-2005057588-A2 GRANULATED DECONTAMINATION FORMULATIONS SANDIA CORPORATION (US) 2005-06-23 WO disclosed
US-20050109981-A1 Decontamination formulations for disinfection and sterilization NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2005-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050109981-A1 Decontamination formulations for disinfection and sterilization CAT, PRKDC, PRKACG FFAR3 3283/4885LCK 3711/4885FYN 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.