Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 19/20 | 0.38 |
| ▸ | PRKCA | P17252 | 18/20 | 0.38 |
| ▸ | PRKCH | P24723 | 18/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 18/20 | 0.38 |
| ▸ | PRKCB | P05771 | 17/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 16/20 | 0.38 |
| ▸ | PIM1 | P11309 | 4/20 | 0.38 |
| ▸ | PRKACA | P17612 | 4/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | PRKACG | P22612 | 2/20 | 0.38 |
| ▸ | PRKACB | P22694 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992220 | 0.86 | PRKCH (0.48) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1991614 | 0.79 | PRKCH (0.57) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1990079 | 0.79 | PRKCH (0.59) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1993950 | 0.76 | PRKCH (0.49) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1993007 | 0.75 | PRKCH (0.45) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1992998 | 0.73 | PRKCH (0.42) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1993004 | 0.73 | PRKCH (0.42) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1996741 | 0.70 | PRKCH (0.75) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1991636 | 0.70 | PRKCH (0.48) | PRKCQPRKCAPRKCHPRKCDPRKCB | |
| SCHEMBL1997849 | 0.69 | PRKCH (0.74) | PRKCQPRKCAPRKCHPRKCDPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | PRKCQ 3598/4885PRKCA 3438/4885PRKCH 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.