Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.69 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6642957 | 0.90 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1999001 | 0.84 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1993872 | 0.84 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1994561 | 0.82 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1994242 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL6640941 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL1996585 | 0.80 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11MET | |
| SCHEMBL25209368 | 0.79 | MAPK14 (0.42) | MAPK14METBUB1CCNB2CDK1 | |
| SCHEMBL30365783 | 0.79 | MAPK14 (0.42) | MAPK14METBUB1CCNB2CDK1 | |
| SCHEMBL2000094 | 0.78 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |