Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994608 | 0.87 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1995900 | 0.85 | TGFBR1 (0.60) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL2891170 | 0.84 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| Hydrochloric Acid SCHEMBL6640025 | 0.84 | TGFBR1 (0.59) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1998794 | 0.83 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1993559 | 0.82 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1996585 | 0.82 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1999001 | 0.82 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1993872 | 0.82 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11PRKD1 | |
| SCHEMBL1992432 | 0.82 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |