SCHEMBL19924522

SCHEMBL19924522

C=C(C)C(=O)OCC(O)CNc1ccc(N)c(-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
FNTA P49354 5/20 0.39
FNTB P49356 5/20 0.39
PGGT1B P53609 4/20 0.39
ADRB2 P07550 8/20 0.38
ADRB1 P08588 7/20 0.38
ADRB3 P13945 6/20 0.38
TDP1 Q9NUW8 2/20 0.37
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR4 O00206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705821 0.82 MAPT (0.48) MAPTTDP1SMN1; SMN2
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL4231187 0.79 MAPT (0.54) MAPTADRB2ADRB1ADRB3HTT
SCHEMBL98079 0.79 MAPT (0.54) MAPTADRB2ADRB1ADRB3HTT
SCHEMBL8064243 0.79 ADRB2 (0.50) MAPTADRB2ADRB1ADRB3HTT
SCHEMBL6572503 0.78 FNTA (0.42) MAPTFNTAFNTBPGGT1BTDP1
SCHEMBL1469210 0.78 MAPT (0.41) MAPTADRB2ADRB1ADRB3HTT
SCHEMBL11650574 0.77 MAPT (0.43) MAPTADRB2ADRB1ADRB3HTT
SCHEMBL10930739 0.77 ADRB2 (0.47) MAPTADRB2ADRB1ADRB3TDP1
SCHEMBL11133924 0.76 BCL2L1 (0.40) MAPTADRB2ADRB1ADRB3SMN1; SMN2
SCHEMBL29813532 0.75 MAPT (0.45) MAPTADRB2ADRB1ADRB3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507331-A1 A LIQUID ANTIOXIDANT COMPOSITION FOR RAW RUBBERS BASF SE (DE) 2019-07-10 EP claimed
WO-2018041649-A1 A LIQUID ANTIOXIDANT COMPOSITION FOR RAW RUBBERS BASF SE (DE) 2018-03-08 WO claimed
WO-2024041977-A1 FLAME-RETARDANT POLYAMIDE COMPOSITION BASF SE (DE) 2024-02-29 WO disclosed
EP-4244286-A1 POLYBUTYLENE TEREPHTHALATE COMPOSITION AND RADAR DEVICE COMPONENT THEREOF BASF SE (DE) 2023-09-20 EP disclosed
WO-2022101399-A1 POLYBUTYLENE TEREPHTHALATE COMPOSITION AND RADAR DEVICE COMPONENT THEREOF BASF SE (DE) 2022-05-19 WO disclosed
CN-108623869-A Sealing element 三菱电线工业株式会社 2018-10-09 CN disclosed
CN-107033798-A Surface protection film, manufacture method and substrate processing layered product 信越化学工业株式会社 2017-08-11 CN disclosed