Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924761 | 1.00 | CTSL (0.42) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL19924759 | 1.00 | CTSL (0.42) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL30396456 | 0.89 | CTSL (0.49) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL25284440 | 0.80 | CTSL (0.50) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL25284441 | 0.80 | CTSL (0.50) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL25243264 | 0.80 | CTSL (0.50) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL25954779 | 0.79 | CAPN1 (0.41) | CTSLCAPN1 | |
| SCHEMBL29015557 | 0.78 | CTSL (0.53) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL25765470 | 0.78 | CTSL (0.53) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL24014373 | 0.78 | CTSL (0.37) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018042343-A2 | COMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | disclosed |