Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924768 | 1.00 | CTSL (0.47) | CTSLCTSBCAPN1 | |
| SCHEMBL19924845 | 0.90 | CTSL (0.53) | CTSLCTSBCAPN1 | |
| SCHEMBL19924846 | 0.90 | CTSL (0.53) | CTSLCTSBCAPN1 | |
| SCHEMBL19924829 | 0.82 | CTSL (0.47) | CTSLCTSB | |
| SCHEMBL19924827 | 0.82 | CTSL (0.47) | CTSLCTSB | |
| SCHEMBL19668587 | 0.81 | CTSL (0.65) | CTSLCTSBCAPN1 | |
| SCHEMBL21114837 | 0.81 | CTSL (0.65) | CTSLCTSBCAPN1 | |
| SCHEMBL19668590 | 0.81 | CTSL (0.65) | CTSLCTSBCAPN1 | |
| SCHEMBL19924892 | 0.80 | CTSL (0.46) | CTSLCTSB | |
| SCHEMBL19924894 | 0.80 | CTSL (0.46) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018042343-A2 | COMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | claimed |
| WO-2018042343-A2 | COMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | disclosed |