Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11790697 | 0.98 | MAPT (0.42) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL28427127 | 0.82 | MAPT (0.44) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL31471657 | 0.81 | MAPT (0.43) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL11406085 | 0.81 | MAPT (0.43) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL28243047 | 0.78 | MAPT (0.41) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL30069566 | 0.77 | LMNA (0.41) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL21590138 | 0.71 | MAPT (0.43) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL29395606 | 0.71 | MAPT (0.43) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL30573 | 0.70 | MAPT (0.42) | MAPTLMNAMAOBRECQLPLIN1 | |
| SCHEMBL29561663 | 0.70 | MAPT (0.42) | MAPTLMNAMAOBRECQLPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110151031-A1 | COMPOSITIONS AND METHODS FOR UTILIZING THE SAME | DBC, LLC (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2010022073-A1 | COMPOSITIONS AND METHODS FOR UTILIZING THE SAME | DBC, LLC (US) | 2010-02-25 | — | — | WO | disclosed |
| US-4055678-A | Sweetener derivatives | DYNAPOL (US) | 1977-10-25 | — | — | US | disclosed |
| US-3976687-A | Sweetener derivatives | DYNAPOL (US) | 1976-08-24 | — | — | US | disclosed |