SCHEMBL19925792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30135074	0.83	PRKCI (0.41)	AXLGPR84PRKCIMAPK1PKM
	SCHEMBL28736869	0.81	KDM4E (0.43)	AXLGPR84PRKCIMAPK1PKM
	SCHEMBL3206828	0.79	CYP2D6 (0.54)	AXLGPR84PRKCIMAPK1PKM
	SCHEMBL1036038	0.77	MAPK1 (0.52)	AXLPRKCIMAPK1PKMJAK2
	SCHEMBL4596460	0.77	LRRK2 (0.42)	AXLGPR84PRKCIPKMJAK2
	SCHEMBL20422633	0.77	JAK2 (0.42)	AXLPRKCIPKMITGB2ICAM1
	SCHEMBL31541397	0.74	PRKCI (0.46)	AXLPRKCIMAPK1PKMJAK2
	SCHEMBL594143	0.74	PRKCI (0.46)	AXLPRKCIMAPK1PKMJAK2
	SCHEMBL4583627	0.73	PRKCI (0.44)	AXLPRKCIMAPK1JAK2DAO
	SCHEMBL19932612	0.73	CCNK (0.44)	AXLPRKCIMAPK1DAOLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.