Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | QPCT | Q16769 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476933 | 0.99 | NOS1 (0.66) | NOS1KDM4ELMNACYP19A1KMT2A | |
| SCHEMBL19925859 | 0.96 | NOS1 (0.61) | NOS1KDM4ELMNACYP19A1KMT2A | |
| SCHEMBL6642525 | 0.96 | QPCT (0.64) | NOS1KDM4ELMNACYP19A1KMT2A | |
| SCHEMBL76423 | 0.92 | KMT2A (0.64) | NOS1KDM4ELMNACYP19A1KMT2A | |
| SCHEMBL19926040 | 0.90 | NOS1 (0.54) | NOS1KDM4ELMNACYP19A1KMT2A | |
| SCHEMBL6104530 | 0.81 | KMT2A (0.64) | NOS1KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9663692 | 0.80 | CYP19A1 (0.80) | CYP19A1KMT2AQPCT | |
| Hydrochloric Acid SCHEMBL2529362 | 0.80 | MEN1 (0.85) | NOS1KDM4ELMNAKMT2AQPCT | |
| SCHEMBL5655099 | 0.80 | CYP19A1 (0.84) | CYP19A1KMT2AQPCT | |
| SCHEMBL10200145 | 0.79 | QPCT (0.91) | NOS1KDM4ELMNAKMT2AQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045106-A1 | ANTI-FUNGAL TREATMENT | OHIO STATE INNOVATION FOUNDATION (US) | 2018-03-08 | — | — | WO | disclosed |