Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | CASP1 | P29466 | 6/20 | 1.00 |
| ▸ | HTR7 | P34969 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | CASP7 | P55210 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | HTR2A | P28223 | 3/20 | 1.00 |
| ▸ | HTR6 | P50406 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harmaline SCHEMBL29626541 | 1.00 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL1360259 | 0.99 | KDM4E (0.97) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL177545 | 0.97 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL30055802 | 0.97 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL31500129 | 0.91 | KDM4E (0.83) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL9481244 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL3877767 | 0.89 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL28061967 | 0.89 | KDM4E (0.78) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL1520427 | 0.85 | KDM4E (0.74) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL28871756 | 0.83 | KDM4E (0.70) | KDM4EMEN1KMT2ACASP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2233 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137652-A1 | Composition Comprising Non-Phosphorylated Tryptamine | SINTALICA S R L (IT) | 2026-05-21 | — | — | US | claimed |
| US-20260091047-A1 | THERAPEUTIC COMBINATIONS FOR MOVEMENT DISORDERS | NATIVE CODE BIO LLC (US) | 2026-04-02 | — | — | US | claimed |
| US-20260034065-A1 | EXTENDED RELEASE PHARMACEUTICAL FORMULATION | DOUGLAS PHARMACEUTICALS LTD (NZ) | 2026-02-05 | — | — | US | claimed |
| US-20250360137-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES INC (US) | 2025-11-27 | — | — | US | claimed |
| US-20250360150-A1 | METHODS OF USING NEUROPLASTIC AGENTS AND TERRAFORMING MARS | BRANNOCK METCALF MOLLY CAROLINE (US) | 2025-11-27 | — | — | US | claimed |
| US-12472146-B2 | Extended release pharmaceutical formulation | DOUGLAS PHARMACEUTICALS, LTD. (NZ) | 2025-11-18 | — | — | US | claimed |
| US-20250339403-A1 | Tryptamine Formulations and Uses Thereof | Natural MedTech Pty Ltd (AU) | 2025-11-06 | — | — | US | claimed |
| EP-4638419-A1 | NON-HALLUCINOGENIC TRYPTAMINE COMPOUNDS, PREPARATION, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sintalica S.r.l. (IT) | 2025-10-29 | — | — | EP | claimed |
| EP-4618981-A1 | COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE | Remedi, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| EP-4618980-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | Freedom Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| EP-1303280-A1 | ENHANCED BRAIN FUNCTION BY GABA-ERGIC STIMULATION | University of Utah Research Foundation (US) | 2003-04-23 | — | — | EP | claimed |
| US-20020192256-A1 | Water miscible pesticide containing a synergistic cocktail of plant alkaloids | GREENTECH, INC. | 2002-12-19 | — | — | US | claimed |
| US-6372239-B1 | Compositions and methods for controlling pests using synergistic cocktails of plant alkaloids | GREENTECH, INC. | 2002-04-16 | — | — | US | claimed |
| US-20020019421-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-02-14 | — | — | US | claimed |
| WO-2002000221-A1 | ENHANCED BRAIN FUNCTION BY GABA-ERGIC STIMULATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2002-01-03 | — | — | WO | claimed |
| WO-2001058263-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PESTS USING SYNERGISTIC COCKTAILS OF PLANT ALKALOIDS | GREENTECH, INC. (US) | 2001-08-16 | — | — | WO | claimed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | claimed |
| US-5591738-A | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof | NDA INTERNATIONAL, INC. (US) | 1997-01-07 | — | — | US | claimed |
| US-5256533-A | Preincubating sample with an alpha-2-inhibitor; comparing fluorescence in test to control tissues | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 1993-10-26 | — | — | US | claimed |
| WO-1991014184-A1 | BETA CARBOLINES AS VITAL STAINS FOR NEUROTRANSMITTER SYSTEMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-09-19 | — | — | WO | claimed |