Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | CASP1 | P29466 | 6/20 | 1.00 |
| ▸ | HTR7 | P34969 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | CASP7 | P55210 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | HTR2A | P28223 | 3/20 | 1.00 |
| ▸ | HTR6 | P50406 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harmaline SCHEMBL199260 | 1.00 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL1360259 | 0.99 | KDM4E (0.97) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL177545 | 0.97 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL30055802 | 0.97 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL31500129 | 0.91 | KDM4E (0.83) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL9481244 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL3877767 | 0.89 | KDM4E (1.00) | KDM4EMEN1KMT2ACASP1HTR7 | |
| Harmaline SCHEMBL28061967 | 0.89 | KDM4E (0.78) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL1520427 | 0.85 | KDM4E (0.74) | KDM4EMEN1KMT2ACASP1HTR7 | |
| SCHEMBL28871756 | 0.83 | KDM4E (0.70) | KDM4EMEN1KMT2ACASP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12263178-B2 | Pharmaceutical compositions and methods | POP TEST ONCOLOGY LLC (US) | 2025-04-01 | — | — | US | claimed |
| EP-3946296-B9 | EXTENDED RELEASE PHARMACEUTICAL FORMULATION | DOUGLAS PHARMACEUTICALS LTD (NZ) | 2024-12-25 | — | — | EP | claimed |
| EP-3946296-B1 | EXTENDED RELEASE PHARMACEUTICAL FORMULATION | DOUGLAS PHARMACEUTICALS LTD (NZ) | 2024-05-01 | — | — | EP | claimed |
| US-20230142627-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | POP TEST ONCOLOGY LLC (US) | 2023-05-11 | — | — | US | claimed |
| EP-2926119-B1 | METHOD OF MARKING OF MATERIAL, MARKED MATERIAL AND METHOD FOR AUTHENTICATING A MATERIAL | SICPA HOLDING SA (CH) | 2023-02-22 | — | — | EP | claimed |
| EP-4313985-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE | Equinorm Ltd (FI) | 2024-02-07 | — | — | EP | disclosed |
| CN-117412975-A | Heterocyclic compounds and their use | 伊科诺姆有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115836058-A | Benzisoxazole derivatives | 住友制药株式会社 | 2023-03-21 | — | — | CN | disclosed |
| WO-2022207979-A2 | NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE | EQUINORM LTD (FI) | 2022-10-06 | — | — | WO | disclosed |
| US-20220169606-A1 | COMPOSITIONS AND COMPOUNDS FOR BIOANALYSIS | SMALL PHARMA LTD. (GB) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169606-A1 | COMPOSITIONS AND COMPOUNDS FOR BIOANALYSIS | BDNF, NEFM, PSMB6 | KDM4E 2655/4885MEN1 1182/4885KMT2A 2685/4885 |
| US-20230142627-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | NR3C2, NR3C1, MC2R | KDM4E 4329/4885MEN1 510/4885KMT2A 3356/4885 |
| US-12263178-B2 | Pharmaceutical compositions and methods | NR3C2, NR3C1, MC2R | KDM4E 4329/4885MEN1 510/4885KMT2A 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.