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Halosulfuron

Halosulfuron

SCHEMBL19926445

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2c(C(=O)O)c(Cl)nn2C)n1.Oc1c(Cl)c(F)nc(F)c1Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.48
▸ CDK1 P06493 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ TP53 P04637 1/20 0.36
▸ GLA P06280 1/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ HTT P42858 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Halosulfuron SCHEMBL66216 0.91 GAA (0.52) GAACDK1MAPTTP53GLA
Halosulfuron SCHEMBL22721319 0.87 GAA (0.48) GAACDK1MAPTTP53GLA
SCHEMBL10673663 0.85 GAA (0.46) GAACDK1MAPTTP53GLA
SCHEMBL55094 0.83 GAA (0.52) GAACDK1MAPTTP53GLA
SCHEMBL13227326 0.83 GAA (0.52) GAACDK1MAPTTP53GLA
Halosulfuron SCHEMBL3374072 0.80 GAA (0.44) GAACDK1MAPTTP53GLA
SCHEMBL3302270 0.80 GAA (0.53) GAACDK1MAPTTP53GLA
SCHEMBL8358886 0.79 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL4453104 0.78 GAA (0.49) GAACDK1MAPTTP53GLA
SCHEMBL8358944 0.78 GAA (0.46) GAACDK1MAPTCYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3506752-A1 PICOLINAMIDES AS FUNGICIDES Dow AgroSciences, LLC (US) 2019-07-10 — — EP disclosed
WO-2018044996-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-03-08 — — WO disclosed