SCHEMBL199273

SCHEMBL199273

c1ccc2c(-c3nccc4ccccc34)nccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.60
CYP2A6 P11509 2/20 0.60
F12 P00748 1/20 0.60
NCF1 P14598 1/20 0.60
NOS3 P29474 1/20 0.60
NOS1 P29475 1/20 0.60
NOS2 P35228 1/20 0.60
BACE1 P56817 1/20 0.60
MAPT P10636 5/20 0.58
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
KDM4E B2RXH2 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
KMT2A Q03164 2/20 0.58
GLA P06280 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
GPR55 Q9Y2T6 1/20 0.53
PLG P00747 1/20 0.48
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29923403 1.00 PLAU (0.60) PLAUCYP2A6F12NCF1NOS3
SCHEMBL30522769 0.97 PLAU (0.58) PLAUCYP2A6F12NCF1NOS3
SCHEMBL13978866 0.90 PLAU (0.56) PLAUCYP2A6F12NCF1NOS3
SCHEMBL12223316 0.90 PLAU (0.56) PLAUCYP2A6F12NCF1NOS3
SCHEMBL12112873 0.88 MAPT (0.58) PLAUCYP2A6F12NCF1NOS3
SCHEMBL4500979 0.87 KDM4E (0.53) PLAUCYP2A6F12NCF1NOS3
Dipyridyl SCHEMBL4596384 0.87 KDM4E (0.56) PLAUCYP2A6F12NCF1NOS3
SCHEMBL50715 0.86 KDM4E (0.66) PLAUCYP2A6F12NCF1NOS3
SCHEMBL29398625 0.86 KDM4E (0.66) PLAUCYP2A6F12NCF1NOS3
SCHEMBL24663020 0.84 MAPT (0.50) PLAUCYP2A6F12NCF1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4526357-A1 FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME University of Houston System (US) 2025-03-26 EP claimed
CN-119143668-A Iron complex based on biisoquinoline and preparation method and application thereof 万华化学集团股份有限公司 2024-12-17 CN claimed
CN-118725264-A Fused heterocyclic polymer containing bisisoquinoline structure and preparation method and application thereof 深圳大学 2024-10-01 CN claimed
US-11976153-B2 Fluorinated polymerization catalysts and methods of making and using the same UNIVERSITY OF HOUSTON SYSTEM (US) 2024-05-07 US claimed
US-20230374171-A1 FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF HOUSTON SYSTEM 2023-11-23 US claimed
WO-2023225216-A1 FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF HOUSTON SYSTEM (US) 2023-11-23 WO claimed
CN-116874421-A Method for synthesizing 1,1' -biisoquinoline derivative from 2, 2-dimethyl-4, 5-diaryl-2H-imidazole 桂林理工大学 2023-10-13 CN claimed
CN-116621777-A Method for synthesizing 1,1' -biisoquinoline oxynitride 桂林理工大学 2023-08-22 CN claimed
US-20190140182-A1 DIBROMO-DIIODO-DIPOLYCYCLIC COMPOUND AND ELECTRON ACCEPTOR MOLECULES DERIVED THEREFROM INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-05-09 US claimed
US-10211402-B2 Dibromo-diiodo-dipolycyclic compound and electron acceptor molecules derived therefrom INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-02-19 US claimed
EP-0355575-B1 Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1994-11-02 EP claimed
EP-0601113-A1 RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE. CIS BIO INT (FR) 1994-06-15 EP claimed
US-5298220-A Forming a coating of a solution containing anioic and cationic dyes and water insoluble organonitrogen compound, drying SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-29 US claimed
EP-0180492-B1 MACROPOLYCYCLIC COMPLEXES OF RARE EARTH METALS AND APPLICATION AS FLUORESCENT LABELS CIS BIO INTERNATIONAL (FR) 1993-06-02 EP claimed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US claimed
WO-1993005049-A1 RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE CIS BIO INTERNATIONAL (FR) 1993-03-18 WO claimed
EP-0479843-A1 BIPYRIDYLES, PROCESS FOR MAKING THEM AND THEIR USE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1992-04-15 EP claimed
WO-1991000276-A1 BIPYRIDYLES, PROCESS FOR MAKING THEM AND THEIR USE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1991-01-10 WO claimed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP claimed
EP-0180492-A1 Macropolycyclic complexes of rare earth metals and application as fluorescent labels CIS BIO INTERNATIONAL (FR) 1986-05-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10211402-B2 Dibromo-diiodo-dipolycyclic compound and electron acceptor molecules derived therefrom WEE2, WEE1, WASF2 PLAU 4663/4885CYP2A6 1755/4885F12 4603/4885
US-20190140182-A1 DIBROMO-DIIODO-DIPOLYCYCLIC COMPOUND AND ELECTRON ACCEPTOR MOLECULES DERIVED THEREFROM WEE2, WEE1, WASF2 PLAU 4663/4885CYP2A6 1755/4885F12 4603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.