Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083717 | 0.89 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14221023 | 0.85 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16697354 | 0.84 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6604256 | 0.84 | SMN1; SMN2 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3222155 | 0.84 | HSP90AA1 (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4769593 | 0.84 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11790304 | 0.83 | HSP90AA1 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3278900 | 0.83 | CYP1A2 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5768324 | 0.83 | HSP90AA1 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10958445 | 0.83 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | NACA, PUF60, POLR1C | RAB9A 3583/4885NPC1 4600/4885SMN1; SMN2 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.