Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992806 | 1.00 | RECQL (0.51) | RECQLALDH1A1SMN1; SMN2SSTR4L3MBTL1 | |
| SCHEMBL1998303 | 0.85 | RECQL (0.53) | RECQLALDH1A1SMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL1992796 | 0.85 | PADI4 (0.45) | SSTR4CNR1ACHECNR2PADI4 | |
| SCHEMBL1992793 | 0.85 | PADI4 (0.45) | SSTR4CNR1ACHECNR2PADI4 | |
| SCHEMBL1997456 | 0.84 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL1992026 | 0.84 | RECQL (0.52) | RECQLALDH1A1SMN1; SMN2SSTR4L3MBTL1 | |
| SCHEMBL1992151 | 0.83 | SMN1; SMN2 (0.48) | RECQLALDH1A1SMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL1992150 | 0.83 | SMN1; SMN2 (0.48) | RECQLALDH1A1SMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL1994342 | 0.83 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2SSTR4L3MBTL1 | |
| SCHEMBL1991515 | 0.83 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | RECQL 3604/4885ALDH1A1 297/4885SMN1; SMN2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.