Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 6/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.45 |
| ▸ | MERTK | Q12866 | 6/20 | 0.45 |
| ▸ | GAS6 | Q14393 | 6/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.40 |
| ▸ | DNM2 | P50570 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17210140 | 0.82 | EGFR (0.56) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL18181915 | 0.79 | MEN1 (0.51) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL16665023 | 0.78 | FLT3 (0.53) | CYP1A2CYP3A4CYP2D6ALOX15CYP2C19 | |
| SCHEMBL19928687 | 0.77 | PRCP (0.47) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL11654039 | 0.76 | ESR1 (0.46) | MEN1KMT2ACYP1A2CYP2D6MERTK | |
| SCHEMBL15114896 | 0.76 | CYP1A2 (0.54) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL20355876 | 0.75 | MEN1 (0.51) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL21016726 | 0.75 | EGFR (0.41) | HRH4HRH3HRH2CYP1A2FLT3 | |
| SCHEMBL19633535 | 0.73 | HRH4 (0.51) | HRH4HRH3HRH2MEN1KMT2A | |
| SCHEMBL15830289 | 0.72 | MEN1 (0.53) | HRH4HRH3HRH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908872-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-03-06 | — | — | US | disclosed |